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Patent

Crescina Transdermic HFSC

  • For thinning hair
  • It helps strengthen and revitalize hair and scalp
  • Hair Scalp Preparation
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Crescina Transdermic HFSC is a topical dermo-cosmetic preparation to help strengthen and revitalize hair and scalp, whose formula benefits from Labo Transdermic Technology: the active ingredients can thus be absorbed by both hair and scalp thanks to their low molecular weight and to the presence of enhancers.

Crescina Transdermic HFSC concentrates in one single vial Labo’s expertise and cutting-edge technology. The formulation contains the core of Crescina, which helps strengthen hair and scalp, and Stem-Engine: both complexes are inserted within specific carriers that allow their gradual and ongoing release into the scalp. The formulation is enriched by the new booster complex, that strengthens the hair and consolidates the activities of the previous complexes, and 3 enhancers, to improve and facilitate the activity of the active ingredients.

With specific formulations for Man and for Woman, it is available in three different dosages to be chosen according to the stage of thinning. Dermatologically tested formula.

20 vials of 3.5 ml each

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A SPECIFIC ANSWER TO THE THINNING PROBLEM

A concentrate of innovation dedicated to your hair's health.

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THE CONCEPT OF CRESCINA

Crescina has always focused on hair and scalp: in fact, Crescina is not just another product that targets the scalp only, it was designed, instead, to help strengthen and revitalize hair and scalp and protect and maintain them in good health.

Crescina vial Ksa
crescina_trasdermic_pic

TECHNOLOGY BEHIND EFFECTIVENESS

Thanks to the Transdermic Technology (Swiss Patent CH 711 466) - inspired by the methodology of aesthetic medicine and patented in 2015 - Labo overcomes the frontiers of the dermo-cosmetic science becoming the first company to develop a new technique of absorption of the active ingredients by hair and scalp, without injections.

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3 USEFUL TIPS

  1. An application of at least two months is recommended, to be repeated twice a year. Where needed, even more cycles can be done, with a month of stop between them.

  2. Apply Crescina on healthy and dry hair scalp.

  3. In the absence of excess sebum, wash your hair at your usual frequency.

11_CRESCINA_HB177_consigli_utili

HOW TO USE THE VIAL

Apply one vial a day for 5 consecutive days on dry hair and follow with a two-day break. Do not rinse.
FOR EXTERNAL USE ONLY. DO NOT INJECT. DO NOT SWALLOW. KEEP OUT OF THE REACH OF CHILDREN.

Illustrazione 1

1. Take the special rigid plastic vial breaker from its holder in the pack.

Illustrazione 2

2. Fit the vial breaker to the vial, simply positioning it over the neck. Grip the vial breaker between finger and thumb and snap off the top part of the vial, applying light but firm pressure.

Illustrazione 3

3. Take the applicator nozzle from its holder.

Illustrazione 4

4. Fit the applicator onto the neck of the opened vial.

Illustrazione 5

5. Remove the cap from the applicator.

Illustrazione 6

6. Apply the preparation to a dry and clean scalp, line by line, concentrating on the areas where thinning is most noticeable. Massage gently to aid the absorption.

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Description and ingredients

CRESCINA TRANSDERMIC HFSC

Crescina Transdermic HFSC includes the basic formulation of Crescina – protected by several patents (total of 7 patents) – combining two amino acids, Cysteine and Lysine with a special strengthening factor, called Glycoprotein, inserted in a hydroalcoholic vehicle. The formula is also characterized by the presence of Stem-Engine: all these active ingredients are inserted within specific carriers (Hydroxypropyl Cyclodextrin) that allow their gradual and ongoing release into the scalp.
The formula has been recently improved thanks to the introduction of Labo patented Transdermic Technology (Swiss Patent CH 711 466) which allows the active ingredients to be absorbed by both hair and scalp, and to the Booster Complex which revitalizes the whole scalp. Finally, 3 enhancers improve and facilitate the activity of the active ingredients.

Crescina is a cosmetic product in vials for topical use, recommended as a hair scalp preparation in specific formulae for Man and Woman. For further information, see the internal leaflet.

INCI

Crescina Transdermic HFSC - 200 - Man: ALCOHOL DENAT., AQUA, GLYCERIN, GLYCINE, METHIONINE, ACETYL CYSTEINE, BENZYL NICOTINATE, PENTYLENE GLYCOL, CAPRYLYL GLYCOL, BUTYLENE GLYCOL, DECYLENE GLYCOL, LYSINE HCL, BENZOPHENONE-4, LAMINARIA DIGITATA EXTRACT, MENTHOL, SILANEDIOL SALICYLATE, TRIETHANOLAMINE, HYDROXYPROPYL CYCLODEXTRIN, THREONINE, SERINE, HYDROLYZED PEA, ZINC ACETYLMETHIONATE, PHOSPHATIDYLCHOLINE, HYDROLYZED RICE PROTEIN, PROPYLENE GLYCOL, ADENOSINE, HEMATITE EXTRACT, HYDROLYZED SOY PROTEIN, GLYCOPROTEINS, ERIOBOTRYA JAPONICA LEAF EXTRACT, HYDROLYZED DNA, HYDROLYZED RNA, GLYCINE SOJA (SOYBEAN) OIL, SODIUM OLEATE, GLUTAMIC ACID, COPPER TRIPEPTIDE-1, ARTEMIA EXTRACT, VALINE, PENTAPEPTIDE-31, HYDROGENATED LECITHIN, DISODIUM EDTA, SORBIC ACID, TRISODIUM EDTA, SODIUM HYDROXIDE, POTASSIUM SORBATE, PHENOXYETHANOL, SODIUM METABISULFITE, ETHYLHEXYLGLYCERIN, SALICYLIC ACID, SODIUM BENZOATE, CI 14720, CI 16255, CI 19140, CI 28440, CI 73015.

Crescina Transdermic HFSC - 200 - Woman: ALCOHOL DENAT., AQUA, GLYCERIN, GLYCINE, METHIONINE, BENZYL NICOTINATE, PENTYLENE GLYCOL, CAPRYLYL GLYCOL, BUTYLENE GLYCOL, DECYLENE GLYCOL, BENZOPHENONE-4, ACETYL CYSTEINE, LYSINE HCL, LAMINARIA DIGITATA EXTRACT, MENTHOL, POLYQUATERNIUM-68, SILANEDIOL SALICYLATE, GLUTAMINE, TRIETHANOLAMINE, HYDROXYPROPYL CYCLODEXTRIN, THREONINE, SERINE, HYDROLYZED PEA, BIOTIN, ZINC ACETYLMETHIONATE, PHOSPHATIDYLCHOLINE, HYDROLYZED RICE PROTEIN, PROPYLENE GLYCOL, ADENOSINE, HEMATITE EXTRACT, HYDROLYZED SOY PROTEIN, PUERARIA MIRIFICA ROOT EXTRACT, GLYCOPROTEINS, ERIOBOTRYA JAPONICA LEAF EXTRACT, HYDROLYZED DNA, HYDROLYZED RNA, GLYCINE SOJA (SOYBEAN) OIL, SODIUM OLEATE, GLUTAMIC ACID, HYDROGENATED LECITHIN, COPPER TRIPEPTIDE-1, ARTEMIA EXTRACT, PENTAPEPTIDE-31, VALINE, SODIUM METABISULFITE, ETHYLHEXYLGLYCERIN, SORBIC ACID, TRISODIUM EDTA, PHENOXYETHANOL, DISODIUM EDTA, SODIUM HYDROXIDE, POTASSIUM SORBATE, SALICYLIC ACID, SODIUM BENZOATE, CI 14720, CI 16255, CI 19140, CI 28440, CI 73015.

Crescina Transdermic HFSC - 500 - Man: ALCOHOL DENAT., AQUA, GLYCERIN, GLYCINE, METHIONINE, LYSINE HCL, BENZYL NICOTINATE, PENTYLENE GLYCOL, CAPRYLYL GLYCOL, BUTYLENE GLYCOL, ACETYL CYSTEINE, DECYLENE GLYCOL, BENZOPHENONE-4, LAMINARIA DIGITATA EXTRACT, GLYCYRRHETINIC ACID, MENTHOL, SILANEDIOL SALICYLATE, HYDROXYPROPYL CYCLODEXTRIN, TRIETHANOLAMINE, THREONINE, SERINE, HYDROLYZED PEA, ALLANTOIN, PROPYLENE GLYCOL, ADENOSINE, ZINC ACETYLMETHIONATE, HYDROLYZED RICE PROTEIN, HEMATITE EXTRACT, PHOSPHATIDYLCHOLINE, GLYCOPROTEINS, HYDROLYZED DNA, HYDROLYZED RNA, ERIOBOTRYA JAPONICA LEAF EXTRACT, GLYCINE SOJA (SOYBEAN) OIL, SODIUM OLEATE, GLUTAMIC ACID, ARTEMIA EXTRACT, COPPER TRIPEPTIDE-1, VALINE, PENTAPEPTIDE-31, HYDROLYZED SOY PROTEIN, HYDROGENATED LECITHIN, SODIUM METABISULFITE, SORBIC ACID, ETHYLHEXYLGLYCERIN, TRISODIUM EDTA, PHENOXYETHANOL, SODIUM BENZOATE, SALICYLIC ACID, DISODIUM EDTA, SODIUM HYDROXIDE, POTASSIUM SORBATE, CI 14720, CI 16255, CI 19140, CI 28440, CI 73015.

Crescina Transdermic HFSC - 500 - Woman: ALCOHOL DENAT., AQUA, GLYCERIN, GLYCINE, METHIONINE, BENZYL NICOTINATE, PENTYLENE GLYCOL, CAPRYLYL GLYCOL, BUTYLENE GLYCOL, DECYLENE GLYCOL, LYSINE HCL, BENZOPHENONE-4, LAMINARIA DIGITATA EXTRACT, GLYCYRRHETINIC ACID, MENTHOL, POLYQUATERNIUM-68, SILANEDIOL SALICYLATE, GLUTAMINE, TRIETHANOLAMINE, HYDROXYPROPYL CYCLODEXTRIN, THREONINE, SERINE, HYDROLYZED PEA, ALLANTOIN, BIOTIN, PROPYLENE GLYCOL, ACETYL CYSTEINE, ADENOSINE, ZINC ACETYLMETHIONATE, HYDROLYZED RICE PROTEIN, HEMATITE EXTRACT, PHOSPHATIDYLCHOLINE, HYDROLYZED SOY PROTEIN, GLYCOPROTEINS, PUERARIA MIRIFICA ROOT EXTRACT, HYDROLYZED DNA, HYDROLYZED RNA, ERIOBOTRYA JAPONICA LEAF EXTRACT, SODIUM OLEATE, GLUTAMIC ACID, ARTEMIA EXTRACT, COPPER TRIPEPTIDE-1, PENTAPEPTIDE-31, GLYCINE SOJA (SOYBEAN) OIL, HYDROGENATED LECITHIN, VALINE, ETHYLHEXYLGLYCERIN, SODIUM METABISULFITE, DISODIUM EDTA, SORBIC ACID, PHENOXYETHANOL, POTASSIUM SORBATE, TRISODIUM EDTA, SODIUM HYDROXIDE, SALICYLIC ACID, SODIUM BENZOATE, CI 14720, CI 16255, CI 19140, CI 28440, CI 73015.

Crescina Transdermic HFSC - 1300 - Man: ALCOHOL DENAT., AQUA, GLYCERIN, GLYCINE, METHIONINE, LYSINE HCL, BENZYL NICOTINATE, PENTYLENE GLYCOL, CAPRYLYL GLYCOL, BUTYLENE GLYCOL, ACETYL CYSTEINE, DECYLENE GLYCOL, BENZOPHENONE-4, LAMINARIA DIGITATA EXTRACT, GLYCYRRHETINIC ACID, MENTHOL, SILANEDIOL SALICYLATE, HYDROXYPROPYL CYCLODEXTRIN, TRIETHANOLAMINE, THREONINE, SERINE, PROPYLENE GLYCOL, HYDROLYZED PEA, ADENOSINE, ALLANTOIN, ZINC ACETYLMETHIONATE, HEMATITE EXTRACT, HYDROLYZED RICE PROTEIN, POTASSIUM SORBATE, PHOSPHATIDYLCHOLINE, HYDROLYZED SOY PROTEIN, GLYCOPROTEINS, HYDROLYZED DNA, HYDROLYZED RNA, ERIOBOTRYA JAPONICA LEAF EXTRACT, GLYCINE SOJA (SOYBEAN) OIL, SODIUM OLEATE, GLUTAMIC ACID, HYDROGENATED LECITHIN, ARTEMIA EXTRACT, PENTAPEPTIDE-31, COPPER TRIPEPTIDE-1, VALINE, DISODIUM EDTA, SODIUM HYDROXIDE, ETHYLHEXYLGLYCERIN, PHENOXYETHANOL, TRISODIUM EDTA, SODIUM METABISULFITE, SORBIC ACID, SALICYLIC ACID, SODIUM BENZOATE, CI 14720, CI 16255, CI 19140, CI 28440, CI 73015.

Crescina Transdermic HFSC - 1300 - Woman: ALCOHOL DENAT., AQUA, GLYCERIN, GLYCINE, METHIONINE, BENZYL NICOTINATE, PENTYLENE GLYCOL, CAPRYLYL GLYCOL, BUTYLENE GLYCOL, LYSINE HCL, DECYLENE GLYCOL, ACETYL CYSTEINE, DISODIUM EDTA, BENZOPHENONE-4, LAMINARIA DIGITATA EXTRACT, GLYCYRRHETINIC ACID, MENTHOL, POLYQUATERNIUM-68, SILANEDIOL SALICYLATE, GLUTAMINE, HYDROXYPROPYL CYCLODEXTRIN, TRIETHANOLAMINE, THREONINE, SERINE, PROPYLENE GLYCOL, HYDROLYZED PEA, ADENOSINE, ALLANTOIN, BIOTIN, ZINC ACETYLMETHIONATE, HEMATITE EXTRACT, HYDROLYZED RICE PROTEIN, PHOSPHATIDYLCHOLINE, HYDROLYZED SOY PROTEIN, GLYCOPROTEINS, HYDROLYZED DNA, HYDROLYZED RNA, PUERARIA MIRIFICA ROOT EXTRACT, ERIOBOTRYA JAPONICA LEAF EXTRACT, GLYCINE SOJA (SOYBEAN) OIL, SODIUM OLEATE, GLUTAMIC ACID, ARTEMIA EXTRACT, COPPER TRIPEPTIDE-1, PENTAPEPTIDE-31, HYDROGENATED LECITHIN, ETHYLHEXYLGLYCERIN, VALINE, SODIUM METABISULFITE, SORBIC ACID, PHENOXYETHANOL, TRISODIUM EDTA, SODIUM HYDROXIDE, SALICYLIC ACID, POTASSIUM SORBATE, SODIUM BENZOATE, CI 14720, CI 16255, CI 19140, CI 28440, CI 73015.

The active ingredients of Labo products may be subject to possible modifications. For an updated version, before using the product, read the list of ingredients on the package.


Technology

TRANSDERMIC TECHNOLOGY

In order for Crescina active ingredients to be absorbed by hair and scalp, Labo researchers developed a technology based on the very low molecular weight of the active ingredients and on the presence of enhancers.

Crescina Transdermic HFSC is a topical dermo-cosmetic preparation to help strengthen and revitalize hair and scalp.
The Patented Transdermic Technology (Swiss Patent CH 711 466) allows the active substances of Crescina, HFSC and Booster Complexes to be absorbed by hair and scalp. Thanks to their low molecular weight and to the presence of 3 enhancers, the functional active ingredients are facilitated in their absorption.

The reported percentages refer to the transdermic absorption of the active substances, in solution, after 24 hours. Transdermic absorption was made possible by the new Labo technology and tested by means of Franz Cells.

Acetyl Cysteine

56.70%

Lysine Hydrochloride

58.30%

Glycoproteins

82.40%

Corosolic Acid

76.90%

Hydrolyzed Rice Protein

84.40%

Methionine

52.30%

Glycine

75.90%

Copper Tripeptide-1

77.00%

Effectiveness

CRESCINA EFFICACY TESTS

Labo carries out several clinical and instrumental tests that support the effectiveness and safety of its preparations.

Below is a summary of some of the most recent tests carried out on Crescina products.

86% of the consumers claim they noticed results in terms of hair revitalization thanks to Crescina formulations

85.8% of the consumers claim they noticed results in terms of hair strength thanks to Crescina formulations Self-assessment test – 8,243 consumers, technical-statistical data processing conducted by Praxidia.

—

93% of the consumers evaluated positively their overall satisfaction after using Crescina products.

88% of the consumers evaluated positively their hair revitalization after using Crescina products.

90% of the testers judged positively Crescina products in relation to the amount of hair.

Self-assessment test – 50 women from AlFemminile community, 2 months of daily use of Crescina Transdermic HFSC

—

+11.5% of healthier hair, after 2 months

+18.3% of healthier hair, after 4 months

Phototrichogram – 46 women, 2/4 months of Crescina HFSC daily use

—

-28% of weak hairs, after 2 months

-43% of weak hairs, after 4 months 95% of the subjects improved after 2 months

100% of the subjects improved after 4 months

Pull test – 42 volunteers, 2/4 months of Crescina HFSC daily use

65.2% of the consumers gave a positive opinion about their hair revitalization

60.9% of them gave a positive opinion about the increased rate in hair revitalization

73.9% of them gave a positive opinion about their hair’s health

82.6% of them gave a positive opinion about the increased strength of their hair

82.6% of them gave a positive opinion about their amount of hair

Self-assessment test – 46 volunteers, 2/4 months of Crescina HFSC daily use

—

91.3% of the consumers are satisfied with hair revitalization results

88.7% of the consumers are satisfied with hair strength increase

Self-assessment test – 230 consumers, 2/4 months of Crescina HFSC use

How to use

HOW TO USE

1. Take the special rigid plastic vial breaker from its holder in the pack.

2. Fit the vial breaker to the vial, simply positioning it over the neck. Grip the vial breaker between finger and thumb and snap off the top part of the vial, applying light but firm pressure.

3. Take the applicator nozzle from its holder.

4. Fit the applicator onto the neck of the opened vial.

5. Remove the cap from the applicator.

6. Apply the preparation to a dry and clean scalp, line by line, concentrating on the areas where thinning is most noticeable. Massage gently to aid the absorption.

Crescina Transdermic HFSC vials contain 3.5 ml of the preparation and are suitable for a daily use during the first 5 days of the week, followed by a 2-day break. The 20 vials included in the box allow for a 1-month application.

Warnings: For external use only. Do not inject. Do not swallow. Avoid contact with the eyes and the mucous membranes. Keep out of the reach of children.

Patents

Crescina Transdermic HFSC was granted 8 patents:

SWISS PATENT CH 703 390

EU PATENT EP 2 561 858

SWISS PATENT CH 693 814

SWISS PATENT CH 693 815

SWISS PATENT CH 697 229

SWISS PATENT CH 711 466

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